Limited time offer
Use code AV15 at checkout for 15% off & Free expedited shipping
Use code AV15 at checkout for 15% off & Free expedited shipping
(Oral GLP‑1)
Needle‑free GLP‑1 confidence—daily tablet routine with clinician guidance.
What it is
Semaglutide, the active ingredient in brand names such as Ozempic, Wegovy, and Rybelsus, offers significant health benefits primarily related to the management of type 2 diabetes, chronic weight management, and the reduction of major cardiovascular and chronic kidney disease risks.
U.S.-Licensed Providers
503A Pharmacy Approved
HIPAA Compliant
Free Discreet Shipping
From $199/mo
As low as $176/month with 6-month plan
4.9
from 2,400+ patients
LegitScript-certified
Licensed in all 50 states
Same GLP‑1 class—simplified daily routine.
Helps you feel satisfied on less, so wins stack up.
Your clinician tunes dose and schedule around your day.
Each of these applies to a specific group. A clinician confirms whether any of them describes you.
Semaglutide helps adults with type 2 diabetes manage their blood sugar levels by stimulating insulin production and reducing the amount of glucose released by the liver.
Approved for
Adults with type 2 diabetes
It is an effective treatment for chronic weight management in people with obesity or who are overweight with a related health condition (e.g., high blood pressure, type 2 diabetes, high cholesterol). This occurs by slowing gastric emptying and targeting brain areas that regulate appetite, leading to increased feelings of fullness and reduced hunger and cravings.
Approved for
Obesity, or overweight with a related condition
In patients with type 2 diabetes or those with obesity/overweight and established heart disease, semaglutide significantly lowers the risk of major adverse cardiovascular events such as heart attack, stroke, or cardiovascular death.
Approved for
Type 2 diabetes, or obesity or overweight with established heart disease
It is approved to reduce the risk of kidney function decline, kidney failure, and death from cardiovascular causes in adults with type 2 diabetes and chronic kidney disease.
Approved for
Adults with type 2 diabetes and chronic kidney disease
Most programs make you wait weeks between labs, review and shipping. We compress the whole thing into a single week.
01 — INTAKE
Tell us about your symptoms and health history. No lab work required to begin.
02 — REVIEW
Your provider reviews your health history and determines whether treatment is appropriate — labs only if your provider needs them.
03 — DELIVERY
If prescribed, your medication ships to your door in days, in plain packaging.
Choose your supply. Everything below is included at both price points.
Month-to-Month
3-Month Plan
$199
/month
Custom compounded medication
$297
/month
$99 per month, 3 months paid up front totaling $297. Personalized Compounded Medication
$99
/month
Billed $99 every month. Cancel anytime.
$960 less per year than monthly
+$35 at-home lab kit, credited to your first month.
Month-to-Month
3-Month Plan
$249
/month
$447
/month
149 per month, 3 months paid up front for 447 total. Personalized Compounded Medication.
$99
/month
Billed $99 every month. Cancel anytime.
$960 less per year than monthly
+$35 at-home lab kit, credited to your first month.
Every number below is what each program advertises publicly — the entry price first, then what that price actually covers.
| Name | Details |
|---|---|
| Ascend Vitality | Starting at $199/mo → As low as $176/mo membership with 6-month plan. |
| RO Body | $45 first month → $145/mo membership (medication extra). |
| Hims | Oral kits from $69/mo with 10‑month prepay; GLP‑1 plans from $199/mo with 6‑month prepay. |
| Eden | GLP‑1 plans $139 first month then $239/mo. |
The meter on each card shows how far the evidence has actually got.
Approved
FDA accelerated approval in adults with moderate to advanced liver fibrosis.
Active trials
Being investigated for slowing cognitive decline in early Alzheimer's disease.
Early studies
Improved insulin sensitivity, weight loss and more regular cycles.
Early signal
Reduced inflammatory markers, with possible benefit to heart, liver and kidneys.
Patient-reported
Reported by some patients following weight loss and better health control.
Semaglutide is a prescription medication and should be used under the guidance of a healthcare professional, alongside a reduced-calorie diet and increased physical activity.
Beyond its primary approved uses, ongoing research is exploring other potential benefits:
Semaglutide has shown anti-inflammatory properties that may benefit the cardiovascular system, liver, and kidneys by reducing inflammatory markers and modulating immune system activity.
Some patients report lower levels of anxiety and depression and improved self-esteem as a result of achieving weight loss and better health control.
Early studies suggest it may help manage PCOS symptoms by improving insulin sensitivity, promoting weight loss, and normalizing menstrual cycles.
Semaglutide has received accelerated FDA approval for the treatment of MASH (formerly known as NASH) in adults with moderate to advanced liver fibrosis.
Researchers are investigating its potential to slow cognitive decline in early Alzheimer’s disease due to its neuroprotective and anti-inflammatory properties.
Straight answers on how Ascend Vitality works, what’s included, and what to expect after checkout.
*Results vary; your plan is individualized.
